JOPIC
Journal of Pulmonology and Intensive Care

The JoPIC is an independent-unbiased, peer-reviewed, and open-access journal of current national and international issues and reviews for original clinical and experimental research, interesting case reports, surgical techniques, differential diagnoses, editorial opinions, letters to the editor, and educational papers in pulmonology, thoracic surgery, occupational diseases, allergology, and intensive care medicine. This journal is indexed by indices that are considered international scientific journal indices (DRJI, ESJI, OAJI, etc.). According to the current Associate Professorship criteria, it is within the scope of International Article 1-d. Each article published in this journal corresponds to 5 points.

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Original Article
Pulmonary vasculer changes in interstitial lung diseases
Abstract
Aims: Pulmonary hypertension (PH) is commonly seen in patients with interstitial lung diseases (ILDs), and is associated with a worse prognosis. The aim of this study was to determine the prevalence of PH in patients with ILDs and identify the markers that may predict this complication without invasive procedures. For this purpose, the correlation between mean pulmonary artery pressures and diffusion test, functional assessments, such as six-minute walk test, was invastigated.
Methods: The study group included 30 patients who were diagnosed interstitial lung disease between February 2010 and February 2011. Demographic and clinical characteristics, physiological studies, sixminute-walking test and high resolution computered tomography results were prospectively collected, and compared between patients with and without PH. Pulmonary hypertension was defined by right heart catheterization and results were compared between patients with PH and with non-PH.
Results: The study cohort consisted of 30 patients, of whom 14 patients (46.6%) had PH. When compared with non-PH subjects, patients with PH exhibited lower six-minutes-walk distance (415 ± 41 m vs. 260 ± 95 m, p <0.001), increased oxygen desaturation percentage during six-minutes-walk test (12.44±5,46 & 7.12±3.48), and decreased percentage of predicted FVC% (49±13.95 & 67±11.56), percentage of predicted FEV1% (52±13.2 & 73.5±12.43), and percentage of predicted DLCO% (38.8±13,7 & 65.3±11.23).
Conclusion: As a result, if there is a doubt about the decrease of pulmonary function tests and exercise capacity, patients with ILDs have to be investigated for pulmonary hypertension. Key Words: Interstitial lung disease, pulmonary hypertension, six-minutes walk test, pulmonary functional tests.

Keywords : Interstitial lung disease, pulmonary hypertension, six-minutes walk test, pulmonary functional tests

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Article available in :
Volume 2, Issue 2, 2024
Page : 23-26
https://doi.org/10.51271/JOPIC-0030
Article Information
Received : 09 Nis 2024
Accepted : 13 May 2024
Published : 23 May 2024
Corresponding Author :

Zeynep Doğrul: Department of Chest Diseases, Süreyyapaşa Chest Diseases and Thoracic Surgery Teaching Hospital, İstanbul, Turkiye

[email protected]
Citation : Doğrul Z, Yıldırım H, Erginel S. Pulmonary vascular changes in interstitial lung diseases. J Pulmonol Intens Care. 2024;2(2):23-26.

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