JOPIC
Journal of Pulmonology and Intensive Care

The JoPIC is an independent-unbiased, peer-reviewed, and open-access journal of current national and international issues and reviews for original clinical and experimental research, interesting case reports, surgical techniques, differential diagnoses, editorial opinions, letters to the editor, and educational papers in pulmonology, thoracic surgery, occupational diseases, allergology, and intensive care medicine.

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Case Report
A rare case of “Inhalation fruit hypersensitivity”
Abstract
Allergies to vegetables and fruits develop as a primary sensitization to pollen allergens followed by cross-reactive secondary sensitization to foods or as a direct sensitization to foods via the gastrointestinal tract. Although much focus has been placed on food hypersensitivity reactions following oral ingestion, reactions resulting from skin contact and inhalation are slowly gaining attention. A 34-year-old female patient, who had no known history of chronic disease and was a teacher by profession, applied to our outpatient clinic with airway symptoms (dyspnea and cough) triggered by apple odor for 5 years. In our test room, where there are equipment that can intervene in a possible anaphylaxis, the patient was provoked with the smell of an apple. The patient was made to smell the apple cut in half for 10 seconds. The patient developed a dry cough that started as mild and then gradually became more severe, and mild urticarial lesions on the anterior chest wall. The patient was diagnosed with inhalation fruit hypersensitivity. An epinephrine auto-injectorwas prescribed and an IKS-LABA dry powder inhaler was prescribed for use when necessary. She was told to stay away from apples.

Keywords : Fruit, hypersensitivity, inhalation

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Article available in :
Volume 3, Issue 2, 2025
Page : 38-39
https://doi.org/10.51271/JOPIC-0054
Article Information
Received : 06 Şub 2025
Accepted : 22 Şub 2025
Published : 29 May 2025
Corresponding Author :

Erdem Emre Gülşen: Department of Immunology and Allergy Diseases, Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkiye

[email protected]
Citation : Gülşen EE, Kalpaklıoğlu AF, Bedir Keser G, Baççıoğlu A. A rare case of “inhalation fruit hypersensitivity”. J Pulmonol Intens Care. 2025;3(2):38-39.

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