JOPIC

The JoPIC is an independent-unbiased, peer-reviewed, and open-access journal of current national and international issues and reviews for original clinical and experimental research, interesting case reports, surgical techniques, differential diagnoses, editorial opinions, letters to the editor, and educational papers in pulmonology, thoracic surgery, occupational diseases, allergology, and intensive care medicine.

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Case Report
A case of desquamative interstitial pneumonia with unidentified etiology
Desquamative Interstitial Pneumonia (DIP) is a rare form of interstitial lung disease, most commonly associated with cigarette smoking. However, in certain cases, environmental, occupational, or immunological factors may play a predominant role. Histopathologically, DIP is characterized by a diffuse and uniform inflammatory process involving the alveolar lumen and interstitium, with the presence of numerous large, mononuclear macrophages in the alveolar spaces and septa. It typically exhibits minimal or moderate septal thickening due to limited collagen deposition and contains few inflammatory cells. Compared to other interstitial pneumonias, DIP generally has a more favorable prognosis. Smoking cessation and corticosteroid therapy have been reported to yield excellent outcomes. Herein, we present a rare case of DIP in a young adult patient with no history of smoking or identifiable environmental exposure, who demonstrated resistance to standard therapy.


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Volume 3, Issue 3, 2025
Page : 86-88
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