JOPIC
Journal of Pulmonology and Intensive Care

The JoPIC is an independent-unbiased, peer-reviewed, and open-access journal of current national and international issues and reviews for original clinical and experimental research, interesting case reports, surgical techniques, differential diagnoses, editorial opinions, letters to the editor, and educational papers in pulmonology, thoracic surgery, occupational diseases, allergology, and intensive care medicine.

eISSN: 2980-0803
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Case Report
Clinical and radiological presentation of multiple intracranial tuberculomas mimicking brain metastases: a case report
Abstract
Cases of brain tuberculoma frequently misdiagnosed as primary or metastatic brain tumors, causes to delay in diagnosis. The delay in diagnosis is even common in patients without a history of pulmonary tuberculosis. In this case report, it is aimed to discuss a patient diagnosed with intracranial tuberculoma mimicking multiple cranial metastases, by focusing on diagnostic challenges and differential diagnosis.

Keywords : Tuberculosis, tuberculoma, intracranial tumor

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1. Sustainable Development Goals [website]. United Nations. 2024.
2. Global strategy and targets for tuberculosis prevention, care and control after 2015 (Resolution WHA67.1, Agenda item 12.1). Geneva: World Health Assembly. 2014.
3. Tiemersma EW, van der Werf MJ, Borgdorff MW, Williams BG, Nagelkerke NJ. Natural history of tuberculosis: duration and fatality of untreated pulmonary tuberculosis in HIV negative patients: a systematic review. PLoS One. 2011;6(4):e17601. doi:10.1371/journal.pone.0017601
4. Saleh M, Saeedi AA, Ali Pooran A. Brain tuberculomas: a case report. Jundishapur J Microbiol. 2014;7(7):e11252. doi:10.5812/jjm.11252
5. Peto HM, Pratt RH, Harrington TA, LoBue PA, Armstrong LR. Epidemiology of extrapulmonary tuberculosis in the United States, 1993-2006. Clin Infect Dis. 2009;49(9):1350-1357. doi:10.1086/605559
6. Rock RB, Olin M, Baker CA, Molitor TW, Peterson PK. Central nervous system tuberculosis: pathogenesis and clinical aspects. Clin Microbiol Rev. 2008;21(2):243-261. doi:10.1128/CMR.00042-07
7. Perez -Malagon CD, Barrera-Rodriguez R, Lopez-Gonzalez MA, Alva-Lopez LF. Diagnostic and neurological overview of brain tuberculomas: a review of literature.Cureus. 2021;13(12):e20133. doi:10.7759/cureus.20133
8. Maltezou HC, Spyridis P, Kafetzis DA. Extra-pulmonary tuberculosis in children. Arch Dis Child. 2000;83(4):342-346. doi:10.1136/adc.83.4.342
9. Fontanilla JM, Barnes A, von Reyn CF. Current diagnosis and management of peripheral tuberculous lymphadenitis. Clin Infect Dis. 2011;53(6):555-562. doi:10.1093/cid/cir454
10. Leonard JM. Central nervous system tuberculosis. Microbiology Spectrum. 2017;5(2). doi:10.1128/microbiolspec.TNMI7-0044-2017
11. Changal KH, Raina AH. Central nervous system manifestations of tuberculosis: a review article. J Mycobact Dis. 2014;4(02):146-150.
12. Katrak SM. Central nervous system tuberculosis. J Neurol Sci. 2021;421: 117278. doi:10.1016/j.jns.2020.117278
13. Wilkinson RJ, Rohlwink U, Misra UK, et al. Tuberculous meningitis. Nat Rev Neurol. 2017;13(10):581-598. doi:10.1038/nrneurol.2017.120
14. Ellard GA, Humphries MJ, Allen BW. Cerebrospinal fluid drug concentrations and the treatment of tuberculous meningitis. Am Rev Respir Dis. 1993;148(3):650-655. doi:10.1164/ajrccm/148.3.650
15. Ramachandran R, Muniyandi M, Iyer V, Sripriya T, Priya B, Govindarajan TG. Dilemmas in the diagnosis and treatment of intracranial tuberculomas. J Neurol Sci. 2017;381:256-264. doi:10.1016/j.jns.2017.08.3258
16. Mansour MA, Ahmadi Z, Ali H, Ayad AA. Intracranial tuberculoma masquerading as a brain tumor: a rare presentation in a healthy young adult with no prior history of tuberculosis. IDCases. 2023;31:e01700. doi:10.1016/j.idcr.2023.e01700
Article available in :
Volume 4, Issue 2, 2026
Page : 23-26
https://doi.org/10.51271/JOPIC-0080
Article Information
Received : 06 Oca 2026
Accepted : 02 Nis 2026
Published : 21 May 2026
Corresponding Author :

Hilal Çalışkan: Department of Anesthesiology and Reanimation, Atatürk Sanatorium Training and Research Hospital, Ankara, Turkiye

[email protected]
Citation : Çalışkan Aydoğan H, Çakıroğlu EB. Clinical and radiological presentation of multiple intracranial tuberculomas mimicking brain metastases: a case report. J Pulmonol Intens Care. 2026;4(2):53-56. doi:10.51271/JOPIC-0080

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